Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables actin binding activity. Acts upstream of or within symbiont entry into host cell. Located in actin filament; clathrin-coated vesicle; and early endosome membrane. Part of AP-3 adaptor complex and CORVET complex. Used to study dystonia. Human ortholog(s) of this gene implicated in dystonia. Orthologous to human VPS16 (VPS16 core subunit of CORVET and HOPS complexes).