Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have calcium ion binding activity. Involved in several processes, including detection of light stimulus involved in visual perception; eye morphogenesis; and neurogenesis. Localizes to apical part of cell; microvillus; and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study Leber congenital amaurosis 8 and retinitis pigmentosa 12. Human ortholog(s) of this gene implicated in pigmented paravenous chorioretinal atrophy and retinal disease (multiple). Orthologous to human CRB1 (crumbs cell polarity complex component 1).