Automated description from the Alliance of Genome Resources
Exhibits thiol-dependent ubiquitin-specific protease activity. Involved in Ras protein signal transduction; endosome organization; and protein deubiquitination. Localizes to the cytosol; extrinsic component of endosome membrane; and midbody. Colocalizes with the acrosomal vesicle. Human ortholog(s) of this gene implicated in ACTH-secreting pituitary adenoma. Orthologous to human USP8 (ubiquitin specific peptidase 8).