Automated description from the Alliance of Genome Resources
Exhibits integrin binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in several processes, including leukocyte migration involved in inflammatory response; myeloid progenitor cell differentiation; and regulation of actin cytoskeleton organization by cell-cell adhesion. Localizes to the Schmidt-Lanterman incisure; bicellular tight junction; and paranodal junction. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Orthologous to human JAM3 (junctional adhesion molecule 3).