Automated description from the Alliance of Genome Resources
Exhibits DNA binding activity. Involved in chromatin organization and negative regulation of transcription by RNA polymerase II. Localizes to the transcriptionally active chromatin. Human ortholog(s) of this gene implicated in precursor lymphoblastic lymphoma/leukemia. Is expressed in early conceptus; embryo; midbrain ventricular layer; and telencephalon ventricular layer. Orthologous to human H1-2 (H1.2 linker histone, cluster member).