Automated description from the Alliance of Genome Resources
Predicted to have chloride channel activity and identical protein binding activity. Predicted to be involved in chloride transport. Predicted to localize to the integral component of plasma membrane. Used to study Bartter disease and Bartter disease type 3. Human ortholog(s) of this gene implicated in Bartter disease type 3; Bartter disease type 4b; Gitelman syndrome; hypertension; and sensorineural hearing loss. Orthologous to several human genes including CLCNKB (chloride voltage-gated channel Kb).