Automated description from the Alliance of Genome Resources
Predicted to have microtubule binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including cell redox homeostasis; negative regulation of angiogenesis; and regulation of establishment of cell polarity. Localizes to the cytoplasm and protein-containing complex. Used to study cerebral cavernous malformation. Human ortholog(s) of this gene implicated in cerebral cavernous malformation and cerebral cavernous malformation 1. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; eye; and reproductive system. Orthologous to human KRIT1 (KRIT1 ankyrin repeat containing).