Automated description from the Alliance of Genome Resources (Release 7.0.0)
Involved in several processes, including apoptotic signaling pathway; negative regulation of mitochondrial membrane potential; and positive regulation of DNA damage response, signal transduction by p53 class mediator. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; positive regulation of apoptotic process; and positive regulation of establishment of protein localization to mitochondrion. Located in mitochondrion. Is expressed in several structures, including brain; genitourinary system; immune system; limb; and liver. Orthologous to human PMAIP1 (phorbol-12-myristate-13-acetate-induced protein 1).