Automated description from the Alliance of Genome Resources
Exhibits extracellular matrix binding activity. Involved in several processes, including extracellular matrix organization; limb development; and positive regulation of cell-substrate adhesion. Localizes to the basement membrane. Used to study microphthalmia with limb anomalies. Human ortholog(s) of this gene implicated in microphthalmia with limb anomalies. Is expressed in several structures, including central nervous system; foot bone; genitourinary system; limb mesenchyme; and oral region epithelium. Orthologous to human SMOC1 (SPARC related modular calcium binding 1).