Automated description from the Alliance of Genome Resources
Exhibits ubiquitin protein ligase activity and ubiquitin protein ligase binding activity. Involved in positive regulation of vasculogenesis and protein autoubiquitination. Localizes to the Cul2-RING ubiquitin ligase complex and Cul5-RING ubiquitin ligase complex. Used to study pre-eclampsia. Orthologous to human ASB4 (ankyrin repeat and SOCS box containing 4).