Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits IkappaB kinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of lipid storage; positive regulation of type I interferon-mediated signaling pathway; and response to type I interferon. Predicted to localize to PML body and mitochondrial membrane. Is expressed in several structures, including future brain; sensory organ; submandibular gland primordium; thymus primordium; and turbinate bone primordium. Orthologous to human IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon).