Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable R-SMAD binding activity; WW domain binding activity; and protein sequestering activity. Involved in negative regulation of SMAD protein signal transduction and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in endosome membrane. Predicted to be active in Golgi membrane and early endosome membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and integumental system. Orthologous to human PMEPA1 (prostate transmembrane protein, androgen induced 1).