Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in cell differentiation; forebrain development; and neural tube closure. Localizes to the nucleus. Is expressed in several structures, including central nervous system; early conceptus; limb mesenchyme; sensory organ; and trunk paraxial mesenchyme. Orthologous to human ZIC5 (Zic family member 5).