Automated description from the Alliance of Genome Resources
Exhibits ATPase inhibitor activity and protein N-terminus binding activity. Involved in several processes, including animal organ development; negative regulation of cell size; and nervous system development. Localizes to the cytoplasm and postsynaptic density. Predicted to colocalize with the actin filament. Used to study autism spectrum disorder; autosomal recessive polycystic kidney disease; and tuberous sclerosis. Human ortholog(s) of this gene implicated in intellectual disability; lymphangioleiomyomatosis; tuberous sclerosis; and tuberous sclerosis 1. Is expressed in several structures, including central nervous system; genitourinary system; hepatic primordium; liver; and retina. Orthologous to human TSC1 (TSC complex subunit 1).