Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits histone binding activity and ubiquitin protein ligase activity. Involved in DNA metabolic process and chromatin organization. Localizes to chromosome, telomeric region; cytoplasm; and nucleus. Is expressed in central nervous system; genitourinary system; nasal cavity epithelium; and thymus primordium. Orthologous to human RNF8 (ring finger protein 8).