Automated description from the Alliance of Genome Resources
Exhibits integrin binding activity. Involved in Rac protein signal transduction; actin cytoskeleton organization; and negative regulation of cell migration. Localizes to the cytosol. Used to study otitis media. Human ortholog(s) of this gene implicated in congestive heart failure. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and retina. Orthologous to human NISCH (nischarin).