Automated description from the Alliance of Genome Resources (Release 4.0)
Enables iron-responsive element binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; cellular response to mercaptoethanol; and cellular response to metal ion. Acts upstream of or within several processes, including intestinal absorption; osteoclast differentiation; and protoporphyrinogen IX biosynthetic process. Located in cytosol. Is expressed in several structures, including nervous system and yolk sac. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human IREB2 (iron responsive element binding protein 2).