Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable guanylate kinase activity; identical protein binding activity; and protein domain specific binding activity. Involved in nervous system development; protein localization to myelin sheath abaxonal region; and regulation of transforming growth factor beta receptor signaling pathway. Acts upstream of or within gene expression; plasma membrane organization; and protein localization. Located in several cellular components, including Schmidt-Lanterman incisure; lateral loop; and myelin sheath adaxonal region. Is active in apical part of cell. Is expressed in several structures, including central nervous system; early conceptus; and eye. Used to study Leber congenital amaurosis. Orthologous to human PALS1 (protein associated with LIN7 1, MAGUK p55 family member).