Automated description from the Alliance of Genome Resources
Exhibits actin filament binding activity and protein homodimerization activity. Involved in centrosome localization; nuclear migration; and regulation of cilium assembly. Localizes to the nuclear envelope. Used to study Emery-Dreifuss muscular dystrophy. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 4; autosomal recessive cerebellar ataxia; bipolar disorder; cerebellar ataxia; and muscular dystrophy. Orthologous to human SYNE1 (spectrin repeat containing nuclear envelope protein 1).