Automated description from the Alliance of Genome Resources
Predicted to have ubiquitin protein ligase activity. Involved in circadian regulation of gene expression and positive regulation of protein ubiquitination. Predicted to localize to the cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Turner type. Orthologous to human HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1).