Automated description from the Alliance of Genome Resources (Release 4.0)
Enables heparin binding activity. Involved in cell adhesion and cellular response to vitamin K. Acts upstream of or within extracellular matrix organization; regulation of Notch signaling pathway; and tissue development. Located in collagen-containing extracellular matrix. Is expressed in several structures, including genitourinary system; heart and pericardium; inner ear; nervous system; and skeleton. Used to study aggressive periodontitis and bone structure disease. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human POSTN (periostin).