Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables GTPase activity; guanyl ribonucleotide binding activity; and identical protein binding activity. Involved in defense response to Gram-negative bacterium; defense response to protozoan; and regulation of autophagy. Acts upstream of or within cellular response to interferon-beta and response to bacterium. Located in endoplasmic reticulum membrane and symbiont-containing vacuole membrane. Is active in cytoplasm. Is expressed in several structures, including foregut; genitourinary system; heart; limb; and respiratory system.