Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable nuclear retinoic acid receptor binding activity and ubiquitin ligase-substrate adaptor activity. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex and chromatin. Predicted to be active in cytoplasm and nucleus. Is expressed in long bone epiphysis. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to several human genes including PRAMEF12 (PRAME family member 12).