Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables chromatin binding activity; histone H3K9 methyltransferase activity; and transcription corepressor activity. Acts upstream of or within corpus callosum morphogenesis; corticospinal tract morphogenesis; and negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; lung; retina; and testis. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 10. Orthologous to human PRDM8 (PR/SET domain 8).