Automated description from the Alliance of Genome Resources
Exhibits NADP binding activity; lithocholic acid binding activity; and steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in oxidation-reduction process. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in 46 XY gonadal dysgenesis; leukemia; precursor B lymphoblastic lymphoma/leukemia; and precursor T-lymphoblastic lymphoma/leukemia. Orthologous to several human genes including AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3).