Automated description from the Alliance of Genome Resources (Release 5.2.0)
Enables cytoskeletal protein binding activity and enzyme binding activity. Involved in regulation of cell projection organization. Acts upstream of or within with a positive effect on cilium organization. Acts upstream of or within embryonic heart tube left/right pattern formation. Located in ciliary basal body; nucleus; and trans-Golgi network. Is expressed in several structures, including brain ventricle and choroid plexus; embryo ectoderm; nasal cavity epithelium; testis; and upper jaw. Orthologous to human PIFO (primary cilia formation).