Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable ubiquitin binding activity; ubiquitin protein ligase activity; and ubiquitin-like protein conjugating enzyme binding activity. Predicted to be involved in several processes, including positive regulation of ERAD pathway; protein ubiquitination; and proteolysis involved in protein catabolic process. Predicted to act upstream of or within autophagy and innate immune response. Predicted to be located in endoplasmic reticulum. Is expressed in central nervous system; genitourinary system; and olfactory epithelium. Orthologous to human RNF185 (ring finger protein 185).