Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of viral transcription; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of NF-kappaB transcription factor activity. Predicted to act upstream of or within immune system process. Predicted to be located in cytoplasmic vesicle and mitochondrial outer membrane. Predicted to be active in cytosol and nucleoplasm. Is expressed in several structures, including central nervous system and genitourinary system. Orthologous to human TRIM14 (tripartite motif containing 14).