Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ceramide phosphoethanolamine synthase activity and sphingomyelin synthase activity. Involved in sphingomyelin biosynthetic process. Acts upstream of or within ceramide biosynthetic process and ceramide phosphoethanolamine biosynthetic process. Predicted to be located in Golgi membrane; nucleoplasm; and plasma membrane. Is expressed in several structures, including alimentary system; nervous system; skeleton; spleen; and white fat. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Orthologous to human SGMS2 (sphingomyelin synthase 2).