Automated description from the Alliance of Genome Resources
Exhibits Lys48-specific deubiquitinase activity; Lys63-specific deubiquitinase activity; and thiol-dependent ubiquitin-specific protease activity. Involved in several processes, including protein deubiquitination; regulation of lymphocyte differentiation; and regulation of signal transduction. Localizes to the ciliary basal body and ciliary tip. Predicted to colocalize with the cytoplasmic microtubule and midbody. Human ortholog(s) of this gene implicated in Brooke-Spiegler syndrome. Is expressed in several structures, including alimentary system; lower urinary tract; nose; pituitary gland; and skin. Orthologous to human CYLD (CYLD lysine 63 deubiquitinase).