Automated description from the Alliance of Genome Resources
Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of MHC class II biosynthetic process and negative regulation of transcription by RNA polymerase II. Predicted to localize to the cytosol; nuclear lumen; and plasma membrane. Is expressed in several structures, including gut; hemolymphoid system gland; integumental system; male reproductive system; and urinary system. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1).