Automated description from the Alliance of Genome Resources
Exhibits protein-glutamine gamma-glutamyltransferase activity. Involved in blood coagulation, fibrin clot formation and peptide cross-linking. Localizes to the collagen-containing extracellular matrix. Used to study factor XIII deficiency. Human ortholog(s) of this gene implicated in artery disease (multiple); factor XIII deficiency; priapism; and thrombophilia (multiple). Orthologous to human F13A1 (coagulation factor XIII A chain).