Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits protein-glutamine gamma-glutamyltransferase activity. Involved in blood coagulation, fibrin clot formation and peptide cross-linking. Localizes to collagen-containing extracellular matrix. Is expressed in several structures, including face; limb; musculature; nervous system; and respiratory system. Used to study factor XIII deficiency. Human ortholog(s) of this gene implicated in artery disease (multiple); factor XIII deficiency; priapism; and thrombophilia (multiple). Orthologous to human F13A1 (coagulation factor XIII A chain).