Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits signaling receptor activity. Involved in negative regulation of cell migration. Localizes to external side of plasma membrane. Is expressed in several structures, including forebrain; genitourinary system; neural retina; and vascular system. Human ortholog(s) of this gene implicated in bicuspid aortic valve disease. Orthologous to human ROBO4 (roundabout guidance receptor 4).