Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to enable phosphatidylinositol phospholipase C activity and small GTPase binding activity. Predicted to be involved in several processes, including diacylglycerol biosynthetic process; intracellular signal transduction; and regulation of signal transduction. Predicted to act upstream of or within lipid catabolic process. Predicted to be located in cytosol; lamellipodium; and plasma membrane. Is expressed in several structures, including facial bone primordium; heart; liver; nervous system; and thymus. Human ortholog(s) of this gene implicated in nephrotic syndrome; nephrotic syndrome type 2; and nephrotic syndrome type 3. Orthologous to human PLCE1 (phospholipase C epsilon 1).