Automated description from the Alliance of Genome Resources
Involved in several processes, including extracellular matrix organization; maintenance of animal organ identity; and non-motile cilium assembly. Localizes to the ciliary base and ciliary inversin compartment. Used to study autosomal dominant polycystic kidney disease and nephronophthisis 3. Human ortholog(s) of this gene implicated in Meckel syndrome 7; Senior-Loken syndrome; nephronophthisis; nephronophthisis 3; and renal-hepatic-pancreatic dysplasia. Orthologous to human NPHP3 (nephrocystin 3).