Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to contribute to guanyl-nucleotide exchange factor activity. Involved in several processes, including behavioral fear response; glutamatergic synaptic transmission; and receptor recycling. Localizes to several cellular components, including lamellipodium; postsynaptic density; and ruffle. Colocalizes with centrosome. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; liver; and retina. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 2. Orthologous to human ALS2 (alsin Rho guanine nucleotide exchange factor ALS2).