Automated description from the Alliance of Genome Resources
Predicted to contribute to guanyl-nucleotide exchange factor activity. Involved in several processes, including behavioral fear response; glutamatergic synaptic transmission; and receptor recycling. Localizes to several cellular components, including the lamellipodium; postsynaptic density; and ruffle. Colocalizes with the centrosome. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 2. Orthologous to human ALS2 (alsin Rho guanine nucleotide exchange factor ALS2).