Automated description from the Alliance of Genome Resources (Release 5.1.1)
Predicted to enable AP-2 adaptor complex binding activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; clathrin coat assembly; and clathrin-dependent endocytosis. Predicted to act upstream of or within endocytosis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in clathrin-coated pit and clathrin-coated vesicle. Is expressed in central nervous system; ganglia; neural retina; and thymus primordium. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human FCHO1 (FCH and mu domain containing endocytic adaptor 1).