Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including regulation of cytokine production; regulation of innate immune response; and response to molecule of bacterial origin. Acts upstream of or within interleukin-1-mediated signaling pathway. Located in cytoplasm and nucleus. Used to study osteoporosis and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IRAK3 (interleukin 1 receptor associated kinase 3).