Automated description from the Alliance of Genome Resources
Involved in epidermis development. Localizes to the cornified envelope. Used to study autosomal recessive congenital ichthyosis 4B. Human ortholog(s) of this gene implicated in ectodermal dysplasia. Is expressed in several structures, including alimentary system; placenta; respiratory system; sensory organ; and skin. Orthologous to human CST6 (cystatin E/M).