Automated description from the Alliance of Genome Resources
Involved in several processes, including brain development; intraciliary retrograde transport; and regulation of smoothened signaling pathway. Localizes to the intraciliary transport particle A. Colocalizes with the nuclear chromatin. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 4 and nephronophthisis 12. Is expressed in central nervous system; embryo ectoderm; limb; and somite. Orthologous to human TTC21B (tetratricopeptide repeat domain 21B).