Automated description from the Alliance of Genome Resources (Release 3.2)
Involved in several processes, including central nervous system development; intraciliary retrograde transport; and regulation of signal transduction. Localizes to intraciliary transport particle A. Colocalizes with nuclear chromatin. Is expressed in central nervous system; embryo ectoderm; limb; and somite. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 4 and nephronophthisis 12. Orthologous to human TTC21B (tetratricopeptide repeat domain 21B).