Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; long-term memory; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including circulatory system development; intracellular signal transduction; and positive regulation of apoptotic process. Located in cytosol and nucleus. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; heart; and maxillary process. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human NFATC4 (nuclear factor of activated T cells 4).