Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits histone methyltransferase activity (H3-K9 specific). Involved in covalent chromatin modification and regulation of histone acetylation. Localizes to nucleus. Colocalizes with Cdc73/Paf1 complex. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 23. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SETD5 (SET domain containing 5).