Automated description from the Alliance of Genome Resources
Exhibits Rab GTPase binding activity and single-stranded telomeric DNA binding activity. Involved in several processes, including negative regulation of DNA recombination at telomere; protection from non-homologous end joining at telomere; and regulation of GTPase activity. Localizes to the nuclear telomere cap complex. Human ortholog(s) of this gene implicated in familial melanoma and malignant glioma. Is expressed in several structures, including genitourinary system; liver; lung; musculature; and spleen. Orthologous to human POT1 (protection of telomeres 1).