Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables N-acetylglucosamine-6-sulfatase activity. Involved in several processes, including esophagus smooth muscle contraction; glomerular filtration; and skeletal system development. Acts upstream of or within several processes, including liver regeneration; positive regulation of canonical Wnt signaling pathway; and regulation of hepatocyte proliferation. Located in plasma membrane. Is expressed in several structures, including embryo mesenchyme; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human SULF2 (sulfatase 2).