Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have serine-type endopeptidase activity. Involved in cellular iron ion homeostasis; negative regulation of BMP signaling pathway; and regulation of transcription by RNA polymerase II. Localizes to plasma membrane. Is expressed in several structures, including cerebral cortex; gut; hemolymphoid system gland; sensory organ; and uterus. Human ortholog(s) of this gene implicated in microcytic anemia. Orthologous to human TMPRSS6 (transmembrane serine protease 6).