Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable ubiquitin ligase complex scaffold activity and ubiquitin protein ligase binding activity. Acts upstream of or within protein catabolic process. Located in nucleolus. Part of Cul2-RING ubiquitin ligase complex. Is expressed in cervical ganglion; cervico-thoracic ganglion; dorsal root ganglion; thoracic ganglion; and trigeminal ganglion. Orthologous to human CUL2 (cullin 2).