Automated description from the Alliance of Genome Resources (Release 4.0)
Is predicted to enable 3'-flap endonuclease activity. Involved in DNA recombination; mitotic intra-S DNA damage checkpoint signaling; and osteoblast proliferation. Acts upstream of or within DNA catabolic process, endonucleolytic; DNA repair; and response to intra-S DNA damage checkpoint signaling. Predicted to be part of Holliday junction resolvase complex. Predicted to be active in nucleus. Used to study Marfan syndrome; arterial tortuosity syndrome; and pulmonary emphysema. Orthologous to human MUS81 (MUS81 structure-specific endonuclease subunit).