Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; enzyme binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including DNA damage checkpoint signaling; cellular response to nerve growth factor stimulus; and cellular response to wortmannin. Predicted to act upstream of or within DNA repair; RNA splicing; and mRNA processing. Predicted to be located in nuclear speck and perinuclear region of cytoplasm. Predicted to be part of DNA replication factor A complex; Prp19 complex; and U2-type catalytic step 2 spliceosome. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and limb. Human ortholog(s) of this gene implicated in osteosarcoma. Orthologous to human CDC5L (cell division cycle 5 like).