Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of intestinal absorption; regulation of transcription by RNA polymerase II; and regulation of vitamin A metabolic process. Predicted to localize to the nucleus. Is expressed in genitourinary system; midgut; and thymus. Orthologous to human ISX (intestine specific homeobox).