Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within negative regulation of intestinal absorption; regulation of transcription by RNA polymerase II; and regulation of vitamin A metabolic process. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; liver; and thymus. Orthologous to human ISX (intestine specific homeobox).