Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including ATP hydrolysis activity; RNA binding activity; and zinc ion binding activity. Involved in innate immune response and response to virus. Acts upstream of or within antiviral innate immune response; protein complex oligomerization; and type I interferon-mediated signaling pathway. Located in cytoplasm. Is expressed in brain. Used to study Aicardi-Goutieres syndrome and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome and primary immunodeficiency disease. Orthologous to human IFIH1 (interferon induced with helicase C domain 1).